Meningioma and levonorgestrel morning-after pill

Meningiomas are typically benign tumors that arise from arachnoid cells, with the majority being intracranial [1] and predominantly affecting women. These tumors are associated with certain conditions, such as neurofibromatosis and the exposure to ionizing radiation.   Since the mid-20th century, a growing body of research has suggested a potential link between the development of […]

Thromboprophylaxis in Pregnancy: A Clinical, Ethical, and Legal Imperative

Thromboprophylaxis in pregnancy has gained greater relevance in recent years due to changes in the profile of pregnant women, with more advanced maternal age and a higher prevalence of comorbidities, which increase the risk of thromboembolic events. Pregnancy and the puerperium are high-risk periods for the development of venous thromboembolic disease (VTE), a potentially fatal […]

A comprehensive approach to diagnosing and managing a fetus with achondrogenesis type 2: A Case Study

Introduction Skeletal dysplasia represents a diverse group of further than 380 disorders characterized by abnormalities in the growth and development of the cartilage and bone. Among these, achondrogenesis is a severe form of skeletal dysplasia, with type 2, also known as Langer- Saldino type, being a rare and lethal variant [1]. Diagnosis of such conditions […]

A rare case of postpartum ovarian vein thrombosis

Introduction Ovarian vein thrombosis is a rare condition that most commonly occurs during pregnancy and the puerperium. It complicates approximately 0.01 to 0.18% of all pregnancies [1]. Caesarean section has been found to increase the risk of ovarian vein thrombosis. In a prospective study performed in a single centre between 2004 and 2007, the incidence […]

Expected performance of genome-wide cell-free DNA testing in pregnancies with a fetus with an isolated nuchal translucency between the 95th-99th percentiles

Introduction Nuchal translucency (NT) is a subcutaneous fluid collection behind the fetal neck that is physiologically present in the first trimester in all fetuses. This measurement is well standardized and so measured by ultrasound between 11+0 and 13+6 weeks of gestation. The association between increased NT and chromosomal abnormalities has been described since 1992 [1-3]. […]

Importance of early diagnosis of sarcoma

Uterine sarcomas (US) are a clinically and histologically heterogeneous group of very rare tumors of mesenchymal origin. They represent approximately 4% of malignant tumors of the uterus and <1% of those of the female genital tract [1]. They are characterized by an aggressive behavior and a poor prognosis. However, prognosis mostly depends on its histological […]

Contraception in transgender people who were assigned a female sex at birth – A Narrative Review

Introduction Gender identity consists in the persistent internal sense of belonging to a certain gender (feminine, masculine, or alternative) [1]. Societies build up and reinforce binarism of gender, but one’s perception of his, her or their identity is what truly determines gender [2]. When there is congruence between biological sex and gender identity, the person […]

Perineal scar endometriosis: Case report

Introduction Perineal scar endometriosis is the presence of endometrial tissue in the superficial perineum. A history of episiotomy, obstetric tear or perianal intervention often associated with curettage is frequently found [1]. It is a very rare entity occurring after only about 0.01% of vaginal deliveries [2]. Episiotomy scar endometriosis is usually diagnosed late due to […]

Endocrinology of ovarian aging: Implications for premature ovarian insufficiency

Introduction The ovary is an organ with a functional capacity limited in time, normally ending around the age of 50, when most women experience natural menopause. The reason for this phenomenon is the depletion of the cellular structures that guarantee the two main functions of the ovary, reproductive and hormonal. These structures, called follicles, are […]

First cases of vNOTES hysterectomy with spinal anesthesia in Wallonia (Belgium)

Introduction The gold standard anesthetic method for vaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy is general anesthesia (GA). GA presents risks and side effects such as postoperative pain, nausea and sometimes vomiting, sore throat and attention disorders. GA is also associated with longer hospital stay. Performing this minimally invasive surgery technique under locoregional anesthesia […]

Impact of violence against women on gynaecological disorders

Introduction Violence against women (VAW) is a pressing global issue that poses a number of significant health risks. Although we currently lack precise data regarding the number of women who have been victims of violence, it is a pervasive social problem, with at least one in four women reaching menopause estimated to have experienced violence […]

Refusal of medical contraception in hypermodern age: does sexuality want to emancipate itself from science?

In Luxembourg, since April 1st, 2023, all means of medical contraception have been fully covered by health insurance for all women. In 2024, according to the European Contraception Policy Atlas, Luxembourg has been declared the best-performing country in terms of online information, funding and counselling. According to mainstream medias, with free contraception for all, Luxembourg […]

Contragestion: Build Back Better

Introduction After over three decades of experience in birth control methods and both medical and surgical pregnancy terminations, I am questioning the scientific representation of human reproductive health. The term “abortion” refers to the expulsion of a fetus from the uterus before it has reached the stage of viability [1]. In human beings, viability occurs usually about the 20th […]

Beyond the pleasure of breastfeeding: Delving into the sexuality of lactating women

Introduction The transition to motherhood and breastfeeding is a vulnerable period in a woman’s life cycle [1], with likely changes in relational and sexual patterns that may affect the couple’s relationship and sexual health [2]. During breastfeeding, there are h changes, including prolactin, estrogen, testosterone and oxytocin that lead to a decrease in desire and […]

An unfortunate case of measles infection in pregnancy mistaken for dengue fever

Introduction In Singapore, measles is an uncommon infection that shares many overlapping clinical features with dengue fever, a viral illness endemic to tropical regions such as Singapore [1]. The COVID-19 pandemic has increased the risk of a global measles outbreak, due to the disruption to measles vaccinations. It is important to raise awareness that the […]

Prenatal diagnosis by exome sequencing: Aicardi-Goutières syndrome: Case report and literature review

Introduction Aicardi-Goutières syndrome is a rare, genetic, early-onset and progressive encephalopathy [1,2]. This disorder results in severe intellectual and physical impairment with microcephaly, dystonia and spasticity [2-5]. Other clinical features include hepatosplenomegaly, chilblains or sterile pyrexias [1-6]. The main findings in neuroimaging are intracranial calcifications of the basal ganglia, white matter changes and cerebral atrophy […]

Challenging antenatal differential diagnosis of a congenital lung malformation. A case report of a hybrid lesion: congenital pulmonary airway malformation type II and bronchial atresia

Introduction Congenital lung malformations are historically rare clinical entities detected in approximately 1 in 10,000 to 35,000 live births [1], with an incidence that tends to increase with, current estimates ranging between 1 in 2,500 to 1 in 8,000 live births [2,3]. They include congenital pulmonary airway malformation (CPAM), previously known as congenital cystic adenomatoid […]

Postnatal maternal re-admission in a district general hospital, England

Introduction Maternal re-admission after childbirth is considered an indicator of the maternal morbidity and quality of care provided by healthcare. This significantly affects the mother-infant bonding and adds to the cost of maternity care. Several studies [1-5] have been undertaken to identify reasons and risk factors for maternal re-admission and various recommendations have been proposed. […]

Report of fertility preservation procedure in a transmasculine person assigned female at birth on testosterone therapy

Introduction Gender dysphoria in transgender people in many cases requires the initiation of safe and effective hormone treatment to develop the physical characteristics of their affirmed gender [1]. Transmasculine people (individuals who identify as men or on the masculine spectrum and were assigned female sex at birth, AFAB) initiate testosterone therapy to achieve the secondary […]

Steroid cell ovarian tumor: A case report and literature review

Introduction Steroid cell tumors are generally unilateral, benign and account for less than 0.1% of all ovarian tumors. Steroid cell tumors have 3 subtypes according to cellular origin: stromal luteoma arising from ovarian stroma, Leydig cell tumor arising from Leydig cells in the hilus, and steroid cell tumor (not otherwise specified, NOS) when the lineage […]