Official Journal of the European Society of Gynecology
eISSN 2710-2580
The multidisciplinary challenge of giant ovarian tumours in postmenopausal morbidly obese women: a case report, review of the literature and meta-analysis
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European Gynecology & Obstetrics
European Society of Gynecology
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Keywords

diagnostic factors, Giant ovarian tumour, prognostic factors, serous borderline cystadenoma, workup algorithm

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How to Cite

Schonäuer, L. M., Cerbone, M., Picardi, N., Cara, I., Damiani, G. R., & Cicinelli, E. (2024). The multidisciplinary challenge of giant ovarian tumours in postmenopausal morbidly obese women: a case report, review of the literature and meta-analysis. European Gynecology & Obstetrics, 6(1). https://doi.org/10.53260/EGO.246012

Abstract

Abstract

Background and aim: giant ovarian tumours (GOTs) in menopause distresses hospital’s medical resources and requires a multidisciplinary team for a successful management.
Methods: case report-data were from our hospital’s records. The literature review was made by PRISMA-methodology and risk-of-bias via modified-ROB2 tools. Statistical analysis was made via IBM-SPSS© software using t-test and chi-squared.
Results: We report the case of radical removal of a 40 cm-30 kg ovarian mass in a 138 kg menopausal woman. The literature review, PROSPERO© pre-registered, assessed 62 cases of menopausal GOTs. Clinical presentation and oncomarkers were often nonspecific, where surgery of choice in 96% of cases laparotomic; mean tumour weight, diameter and volume were 23 kg, 29 cm and 11,777 cm3, respectively. 56% of tumours were malignant and 23% borderline. Ascites and acute abdomen were significantly associated with malignancy (p<0.01) while tumours of high diameter were more likely benign (p<0.03). Among malignancy, high-weigh high-volume tumours were more commonly borderline (p<0.01). Conclusions: The study underlines the need of a multidisciplinary team to manage giant ovarian neoformations in menopause successfully. Middle- and high-specialisation gynaecological oncologic centres should have protocols and guidelines to diagnose and manage those pathologies.

https://doi.org/10.53260/EGO.246012%20
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Copyright (c) 2024 Luca M. Schonäuer, Marco Cerbone, Nico Picardi, Iris Cara, Gianluca R. Damiani, Ettore Cicinelli