Official Journal of the European Society of Gynecology
eISSN 2710-2580
Influence of the onset of menopause before and after age 50 on bone mineral density
Logo EGO
European Gynecology & Obstetrics
European Society of Gynecology
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Keywords

body composition, bone mineral density, dual energy X-ray absorptiometry, fracture, Menopausal age

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How to Cite

de Matos, O., Lenardt, B., de Lima, I. C., Strapasson Furlan, G. A., Yamaguishi, T., Lass, A. D., & Castelo-Branco, C. (2023). Influence of the onset of menopause before and after age 50 on bone mineral density. European Gynecology & Obstetrics, 5(1). https://doi.org/10.53260/EGO.235014

Abstract

Aim: To evaluate the effect of menopause on bone mineral density (BMD) considering the time of onset of this event in women participating in an exercise program for elders.
Methods: A total of 153 Brazilian postmenopausal women aged 65.6 ± 8.1years were included in this study. All participants were postmenopausal women as defined by the modified Reproductive Aging Workshop (STRAW) staging system. Dual-energy X-ray absorptiometry was used to determine BMD, fat and muscle percentage and distribution. For statistical analysis, the sample was divided into two groups, BA: menopause before age of 50 (inclusive) and AA: menopause after the age of 50.
Results: The correlation and regression analysis demonstrated that for the BA group total mass had a significant influence on BMI (78%), percentage of fat (52%) andandroid/gynoid relation (17%). BMI had influence on percentage of fat (57%) and android/gynoid relation (17%). Hip T-score influenced only with percentage of fat (4.5%). For the AA group, mass also showed an important influence, but only with age at menopause (9.5%) and BMI (87%). The OR for having lower BMD in group BA was 0.82 indicating a lower risk.
Conclusion: Despite similar results between the studied groups, the menopause group before 50 years of age showed the greatest associations between variables and influence on BMD, especially in hip area.

https://doi.org/10.53260/EGO.235014%20
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Copyright (c) 2026 Oslei de Matos, Brenda Lenardt, Isabela C. de Lima, Gabriel A. Strapasson Furlan, Tsuani Yamaguishi, André Domingos Lass, Camil Castelo-Branco